Could you help with the use of the phrase "not least" in this sentence?

Acute and chronic pain syndromes in pregnant women are difficult to manage, not least because there is a need to balance the best interests of the mother and the neonate.

Please explain the exact meaning and the use of "not least" in this sentence.

It does not necessarily mean the most important aspect, but does not mean the least important aspect either. It means it’s a mid-level concern, yet noteworthy.

5 Responses to “Could you help with the use of the phrase "not least" in this sentence?”

  1. Helen Scott Says:

    it’s like saying ‘mostly’.
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  2. Milo Says:

    It means "largely" or "a big reason".
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  3. ☆ Spharoe Says:

    It does not necessarily mean the most important aspect, but does not mean the least important aspect either. It means it’s a mid-level concern, yet noteworthy.
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  4. Skywalker Says:

    One important reason for managing the pain, but not the least important reason, is because it is in the best interest of the mother and the neonate. Does this now make more sense ?
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  5. Trish Says:

    In this sentence, "not least" means that the balance of needs of the mother and neonate is not the smallest of concerns, but by implication is a MAJOR concern in pain management.
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